Biochemical Effects of Fluoride and Metal Ingestion

Toxic fluoride affects ALL of us. And did you know that fluoride additives used in the water fluoridation process are another potential source for metal ingestion by humans?

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Aluminum is a chemical element with symbol Al and atomic number 13.

The combination of aluminum and fluoride in products like drinking water, toothpaste, and medications has been a hot topic regarding potential health risks. Here are some key points to consider:

Fluoride and Aluminum Interaction  

• Fluoride can increase the bioavailability of aluminum, meaning it may help aluminum be absorbed into the body more easily.

• Aluminum fluoride complexes can form when both elements are present, potentially impacting how aluminum is metabolized.

Potential Health Risks  

• Neurotoxicity: Studies are stating that aluminum, especially in the presence of fluoride, may contribute to neurodegenerative diseases like Alzheimer’s disease.

Below is important information we want to feature from Dr. Sandra Young. This is what she submitted to Secure Arkansas regarding aluminum and the effects on our bodies:

Dear Senators and Representatives,

I have written some additional information about fluoride that I do not think you have heard.  It is below.  Please at least skim this.

Biochemical Effects of Fluoride and their Drug Costs

Fluorine F is the most reactive element and binds with all other elements except for the light noble gases. It is never found as a free element in nature. Soluble metal fluorides are very active biologically.

Fluoride inhibits enzymes which was well-known in the 1950s. James Sumner PhD of Cornell University won the Nobel Prize for his work in enzyme chemistry. He opposed fluoridation and is quoted as saying, “We ought to go slowly. Everybody knows fluorine and fluorides are very poisonous substances, and we use them in enzyme chemistry to poison enzymes, those vital agents in the body. That is the reason things are poisoned, because the enzymes are poisoned, and that is why animals and plants die.”

Dean Burk PhD is a biochemist, medical researcher, and cancer researcher at the Kaiser Wilhelm Institute and the National Cancer Institute. After retiring from the NCI in 1974, he continued to oppose water fluoridation. He did a study showing that within 5 years after a city fluoridated their water, there was a 20% increase in cancer mortality. He regarded fluoridation as “mass murder on a grand scale.” 

See this video: Fluoride Causes Cancer – Dr Dean Burk Ph.D

Fluoride interferes with hydrogen bonding, which is weaker than co-valent bonding but holds molecules and DNA in their 3-D shape. Shape and function are intimately connected. There are two complex ions that are very important. They are silicon hexafluoride SiF62- and aluminum tetrafluoride AlF4-, a phosphate mimic. I believe that it is as the phosphate mimic that aluminum (Al) is transported across the blood-brain barrier. See this: Signaling mechanistics: Aluminum fluoride for molecule of the year.

Aluminum is the third most abundant element after oxygen and silicon. Hexafluorosalicic acid is the compound added to our water for fluoridation. We ingest aluminum when we drink from aluminum cans and/or eat from food prepared in aluminum cookware or wrapped in aluminum foil. Some foods contain aluminum. See this from Children’s Hospital of Philadelphia, Vaccine Education Center: Vaccine Ingredients: Aluminum.

Messengers are sent to cells to activate cellular responses. Messengers are light-sensitive compounds, odors, pheromones, hormones and neurotransmitters. The messages are transported into the cells.  G protein-coupled receptors (GPCRs) are the largest family of membrane receptors/transmitters that are targeted by approved drugs. See this: G protein-coupled receptor . Aluminum tetrafluoride plays a big role in blocking this message. Phyllis Mullenix PhD explains how in this video: Phyllis Mullenix, PhD discusses the toxicity of water fluoridation at IAOMT 2009 Las Vegas.  Notice at the end of the cAMP cycle when ATP releases a phosphate to become ADP, rather than a phosphate being released, it is aluminum tetrafluoride. ATP is the main energy source of our cells. If ATP is not releasing the phosphate, would that not be the cause of chronic fatigue? (my thoughts)  From the National Library of Medicine, PubMed Central: G Protein-Coupled Receptors as Targets for Approved Drugs: How Many Targets and How Many Drugs?  This paper says that approximately 35% of all drugs in 2018 targeted GPCRs. In 2006 Insights into Receptor Function and New Development Targets, Springer stated that GPCR drugs accounted for approximately $40 billion in sales and of all the drugs at market, approximately 70% targeted GPCR function. Two other articles state that in 2014 ~50% of drugs and in 2015 60% of drugs target GPCR function.

How much Medical dollar $ savings would there be if we did not have aluminum fluoride requiring drugs to correct the diseases they cause?

There are multiple references suggesting that aluminum is the cause of Alzheimer’s Disease. And that fluoride is the transporter of aluminum into the brain. One of these is Kawahara’s Link between aluminum and the pathogenesis of Alzheimer’s Disease.  

Another is at Fluoride Alert: “Is dementia caused by aluminum through fluoridation?“  

Also, Anna Choi: Developmental Fluoride Toxicity.

Varner’s study showed that rats fed for 1 year with water containing either sodium fluoride or aluminum fluoride had beta-amyloid deposits (found in Alzheimer’s patients) in their brain.

An independent source of information about fluoride in our drinking water is at Fluoride in Drinking Water: A Scientific Review of EPA’s Standards (2006.)  Notice that each chapter ends with the request for additional research.

Additional information about specific diseases can be found at Fluoride Alert: Health Effects of Fluoride.

Respectfully,

Sandra Sindel Young, MD (retired)

[email protected]

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Also, here’s another great study performed by Dr. Phyllis Mullenix regarding more dangerous metals in the raw fluoridation chemicals/ additives, such as aluminum and others, that are other contaminants we’ve been talking about in our previous articles.

Here is the background from Dr. Mullenix’s study:

Fluoride additives contain metal contaminants that must be diluted to meet drinking water regulations. However, each raw additive batch supplied to water facilities does not come labeled with concentrations per contaminant. This omission distorts exposure profiles and the risks associated with accidents and routine use.

The result found:

Results show that metal content varies with batch, and all HFS samples contained arsenic (4.9–56.0 ppm) or arsenic in addition to lead (10.3 ppm). Two NaF samples contained barium (13.3–18.0 ppm) instead. All HFS (212–415 ppm) and NaF (3312–3630 ppm) additives contained a surprising amount of aluminum.

The conclusion:

Such contaminant content creates a regulatory blind spot that jeopardizes any safe use of fluoride additives.

In closing, the aluminum content, along with other contaminants in fluoride additives, is significant and varies between batches. We need to take action to limit our hazardous exposures, especially in our drinking water.

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